Research Fellow

 

 

 

 

 

Address:

Center of Chemistry, Faculty of Chemistry University of Belgrade,
Studentski trg 14-16/I, lab. 463, 11158 Belgrade 118, PAK 105104, Serbia
Telephone: 011-3336-759
Fax: 011-2636-061
E-mail: srkostic@chem.bg.ac.rs

Education:

1990 B.Sc.,Chemistry
1994 M.Sc.,Chemistry
1998 Ph.D.,Chemistry

Research Ranks:

1991 Research Trainiee
1995 Research Assistant
1998 Research Associate / Assistant Research Professor
2004 Senior Research Associate / Associate Research Professor
2009 Principal Research Fellow / Full Research Professor

Memberships:

Serbian Chemical Society
2010 – 2013 – Professional board – University of Belgrade
2014- Governing board – ICTM

Professional Experience:

1991 – ICTM – Center of Chemistry
2016 – Head of Center

Research Interests:

Organic Chemistry and Biochemistry. Synthesis of heterocyclic compounds and biochemical caracterisation of newly synthesized ligands.
Computational chemistry, investigation of ligand-receptor interactions.

Language Skills: english

Projects:

Basic Research:
1991-2001 Testing of natural products from local plants and animals and the earth's crust - sub-project: The
design, synthesis and biological activity of dopaminergic agonists and antagonists, and
anticoagulants
2002-2006 Modeling and synthesis of heterocyclic compounds with biological activity (project leader)
2006-2010 Synthesis and characterization of biologically active substances and computer simulation of
biological systems (project leader)
2011 – Study of structure-activity relationship of newly synthesized biologically active substances
(project leader)

Major Publications:

Published papers:

1. Jelena Z. Penjišević, Vladimir V. Šukalović, Deana B. Andrić, Goran M. Roglić, Vukić Šoškić and Slađana V.   Kostić-Rajačić, Synthesis, Biological, and Computational Evaluation of Substituted 1-(2-Methoxyphenyl)-4-(1-phenethylpiperidin-4-yl)piperazines and 1-(2-Methoxyphenyl)-4-[(1-phenethylpiperidin-4-yl)methyl]piperazines as Dopaminergic Ligands (2016), DOI:10.1002/ardp.201600081 2
2. Sukalovic Vladimir B,  Soskic Vukic,   Kostic-Rajacic Sladjana V , Modeling of Dopamine D2 Receptor -     Overview of 35-Year Evolution, Current Medicinal Chemistry, (2015),  22 (25),  2972-2990
3. Soskic Vukic,  Sukalovic Vladimir B,  Kostic-Rajacic Sladjana V , Exploration of N-arylpiperazine Binding Sites of D2 Dopaminergic Receptor, Mini Reviews in Medicinal Chemistry, (2015),  15 (12),  988-1001
4. Marjan Popovic, Zeljka Stanojevic, Jelena Tosic, Aleksandra Isakovic, Verica Paunovic, Sasa Petricevic, Tamara Martinovic, Darko Ciric, Tamara Kravic-Stevovic, Vukic Soskic, Sladjana Kostic-Rajacic, Kaveh Shakib, Vladimir Bumbasirevic , Vladimir Trajkovic,  Neuroprotective arylpiperazine dopaminergic/serotonergic ligands suppress experimental autoimmune encephalomyelitis in rats, J. Neurochem., (2015), 135 (1), 125-138
5. Sencanski Milan V,  Sukalovic Vladimir B,  Shakib Kaveh,  Soskic Vukic,  Dosen-Micovic Ljiljana I,  Kostic-Rajacic Sladjana V , Molecular Modeling of 5HT(2A) Receptor - Arylpiperazine Ligands Interactions, Chem Biol Drug Des, (2014),  83 (4),  462-4713967-3972