IHTM PLAVI
University of Belgrade
Institute of Chemistry, Technology and Metallurgy
National Institute of the Republic of Serbia

grb BUUniversity of Belgrade

Irena Novaković, Ph.D.

Research Associate

 

 

 

 

Address:

ICTM-Center for Chemistry, Laboratory for Bioorganic and Medicinal chemistry,
Faculty of chemistry, Studentski trg 12-16, 1st floor, lab 481
11158 Belgrade, PAC 105104, Serbia Telephone: +381113336683
Fax: +381112636061
GSM: +381691516441
E-mail: irenan@chem.bg.ac.rs

Education:

2000. Chemist, bachelor of science
2005. Master of chemistry
2012. Ph.D. of chemical sciences

Research Ranks:

2005. Research Trainiee
2013. Research Associate

Memberships: Member of Serbian Chemical Society

Professional Experience: 2001.– present ICTM – Center for Chemistry

Research Interests:

Sinthesys of biologically active oraganic compounds, Isolation of natural products from marine organisms, Modifications of biomacromolecules, Antioxidative and antimicrobial activity of biological active compounds

Language Skills: Serbian, English, Russian

Projects:

Basic Research:
2011-2014. Interactions of natural products, its derivatives and complex compounds with proteins and nucleic acid
International Research:
2012-2013. Structural transitions of proteins and their recognition by small molecules: Thermodynamics in correlation with functionality

Major Publications:

Published Papers:

  1. Jovana Vilipić,  Irena Novaković,  Tatjana Stanojković,  Ivana Matić,  Dejan Šegan, Zoran Kljajić, Dušan Sladić, Synthesis and biological activity of amino acid derivatives of avarone and its model compound Bioorg. Med. Chem., 23, 6930-6942, 2015
  2. Miroslav Novaković, Irena Novaković, Mirjana Cvetković, Dušan Sladić,  Vele Tešević, Antimicrobial activity of the diarylheptanoids from the black and green alder, Brazilian Journal of Botany, 38, 441-446, 2015
  3. Irena Novaković, Uroš Anđelković, Mario Zlatović, Miroslav J. Gašić and Dušan Sladić, Bioconjugate of lysozyme and the antibacterial marine sesquiterpene quinone avarone and its derivatives, Bioconjugate Chem., 23, 57-65, 2012
  4. Natalija M. Krstic, Mira S. Bjelakovic, Vladimir D. Pavlovic, Robeyns Koen, Zorica D. Juranic, Ivana Z. Matic, Irena T. Novakovic and Dusan M. Sladic, New androst-4-en-17-spiro-1,3,2-oxathiaphospholanes. Synthesis, assignment of absolute configuration and in vitro cytotoxic and antimicrobial activities, Steriods, 77, 558-565, 2012
  5. Irena T. Novakovic, Jelena Penjisevic, Vladimir V. Sukalovic, Deana B. Andric, Goran M. Roglic and Sladjana V. Kostic-Rajacic, Investigation of Antibacterial Activity of Cinnamyl Derivatives of Arylpiperazine, Arch. Biol. Sci., 64, 15-20, 2012
  6. Tatjana Božić, Irena Novaković, Miroslav J. Gašić, Zorica Juranić, Tatjana Stanojković, Srdjan Tufegdžić, Zoran Kljajić and Dusan Sladić, Synthesis and biological activity of derivatives of the marine quinone avarone, Eur. J. Med. Chem. 45, 923-929, 2010
  7. N. Filipović, H. Borrmann, T. Todorović, M. Borna, V. Spasojević, D. Sladić, I. Novaković, K. Anđelković,  Copper(II) complexes of N-heteroaromatic hydrazones: Synthesis, X-ray structure, magnetic behavior and antibacterial activity, Inorg. Chim. Acta, 362, 1996-2000, 2009
  8. I. Pajić, Z. Vujčić, M. Vujčić, I. Novaković, D. Sladić, M. J. Gašić, Chemical modification of the lectin of the marine coral Gerardia savaglia by marine quinone avarone,  J. Serb. Chem. Soc. 72, 1271-1274, 2007
  9. M. Tsoukatou, J.P. Maréchal, C. Hellio, I. Novaković, S. Tufegdžić, D. Sladić, M.J. Gašić, A.S. Clare, C. Vagias, V. Roussis, Evaluation of Activity of the Sponge Metabolites Avarol and Avarone and their Synthetic Derivatives Against Fouling Micro- and Macroorganisms, Molecules, 12, 1022-1034, 2007
  10. K. Penov-Gaši, M. Đurendić-Brenesel, E. Đurendić, M. Sakač, J. Čanadi, J. Daljev, T. Armbruster, S. Andrić, D. Sladić, T. Božić, I. Novaković, Z. Juranić, Synthesis and biological evaluation of some 17-picolyl and 17-picolinylidene androst-5-ene derivatives, Steroids 72, 31-40, 2007
  11. N. Milosavić, R. Prodanović, S. Jovanović, I. Novaković, Z. Vujčić, Preparation and characterization of two types of covalently immobilized amyloglucosidase, J. Serb. Chem. Soc. 70, 713-719, 2005
  12. D. Sladić, I. Novaković, Z. Vujčić, T. Božić, N. Božić, D. Milić, B. Šolaja, M. J. Gašić, Protein covalent modification by biologically active quinones, J. Serb. Chem. Soc. 69, 901-907, 2004
  13. I. Novaković, Z. Vujčić, T. Božić, N. Božić, N. Nilosavić, D. Sladić, Chemical modification of beta-lactoglobulin by quinones, J. Serb. Chem. Soc. 68, 243-248, 2003
  14. T. Božić, D. Sladić, M. Zlatović, I. Novaković, S. Trifunović, M.J. Gašić, Regioselectivity of conjugate additions to monoalkyl-1,4-benzoquinones, J. Serb. Chem. Soc. 67, 547-551, 2002